COL11A1

Across TCGA cell cohorts, COL11A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,044 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COL11A1-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Response to hydrostatic pressure, and Negative regulation of calcium ion export across plasma membrane. Each is linked with COL11A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL11A1-to-partner and partner-to-COL11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by COL11A1-low versus COL11A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL11A1→partner) and Y-score (partner→COL11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein-containing complex assembly →	+0.085	+3.404	.001	.002	3	6
BONE	Response to hydrostatic pressure →	+0.165	+3.543	.001	.001	3	6
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.050	+2.672	.001	.003	3	6
LIVER	Membrane protein proteolysis →	+0.095	+2.988	.003	.002	3	5
LIVER	Actin polymerization-dependent cell motility →	+0.189	+4.298	.002	.008	3	5
BREAST	Cellular response to type I interferon →	+0.092	+0.202	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,044 associations by consensus.

Negative regulation of protein-containing complex assembly by COL11A1 expression — BONE

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