COL11A1

Across TCGA cell cohorts, COL11A1 mutation is significantly associated with the RNA expression of many other genes, with 1,953 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL11A1-associated genes across cancer lineages are TRAT1, GPR119, and IER3. Each is linked with COL11A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL11A1-to-partner and partner-to-COL11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAT1 grouped by COL11A1-low versus COL11A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL11A1→partner) and Y-score (partner→COL11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TRAT1 →	+2.347	+4.169	<.001	<.001	3	3
BREAST	GPR119 →	+0.017	+4.378	<.001	<.001	3	3
LUNG_SCLC	IER3 →	+1.740	+3.169	<.001	.003	3	3
UPPER_AERODIGESTIVE_TRACT	ANP32D →	+0.090	+2.786	<.001	.004	2	4
LARGE_INTESTINE	STX10 →	+0.530	+2.351	.003	.001	3	3
LARGE_INTESTINE	PRDM4 →	+0.459	+3.459	.001	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,953 associations by consensus.

TRAT1 by COL11A1 expression — BLOOD_Leukemia

Explore this box plot interactively →