COIL

Across TCGA patient cohorts, COIL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,654 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COIL-associated proteins across cancer lineages are VEZF1, WIZ, and XAB2. Each is linked with COIL in more than 7 cancer types. Because this analysis shows association rather than direction, both COIL-to-partner and partner-to-COIL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COIL versus VEZF1 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COIL→partner) and Y-score (partner→COIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VEZF1 →	+0.450	+0.469	<.001	.003	3	8
LSCC	WIZ →	+0.242	+0.463	<.001	<.001	3	6
LSCC	XAB2 →	+0.303	+0.506	<.001	<.001	3	6
GBM	XRCC1 →	+0.374	+0.423	<.001	<.001	3	6
LSCC	ZNF830 →	+0.333	+0.596	<.001	<.001	3	6
LSCC	BPTF →	+0.310	+0.661	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,654 associations by consensus.

COIL vs VEZF1 — HNSC

Explore this scatter interactively →