COG6

Across TCGA patient cohorts, COG6 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COG6-associated proteins across cancer lineages are COG1, COG3, and COG4. Each is linked with COG6 in more than 9 cancer types. Because this analysis shows association rather than direction, both COG6-to-partner and partner-to-COG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COG6 versus COG1 in BRCA, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COG6→partner) and Y-score (partner→COG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COG1 →	+0.389	+0.403	<.001	<.001	3	10
BRCA	COG3 →	+0.487	+0.440	<.001	<.001	3	10
BRCA	COG4 →	+0.394	+0.413	<.001	<.001	3	10
BRCA	COG5 →	+0.361	+0.379	<.001	<.001	3	10
BRCA	COG7 →	+0.405	+0.380	<.001	<.001	3	10
BRCA	COPA →	+0.258	+0.338	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,028 associations by consensus.

COG6 vs COG1 — BRCA

Explore this scatter interactively →