COG5

Across TCGA patient cohorts, COG5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,425 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COG5-associated proteins across cancer lineages are MEPCE, TNPO3, and PDAP1. Each is linked with COG5 in more than 5 cancer types. Because this analysis shows association rather than direction, both COG5-to-partner and partner-to-COG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COG5 versus MEPCE in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COG5→partner) and Y-score (partner→COG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEPCE →	+0.302	+0.545	<.001	.001	3	6
GBM	TNPO3 →	+0.288	+0.289	<.001	.001	3	6
COAD	PDAP1 →	+0.356	+0.461	<.001	<.001	3	5
OV	PRKRIP1 →	+0.352	+0.485	.006	.004	2	6
HNSC	PNPLA8 →	+0.403	+0.634	<.001	<.001	3	5
BRCA	EIF4H →	+0.251	+0.729	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,425 associations by consensus.

COG5 vs MEPCE — HNSC

Explore this scatter interactively →