COG5

Across TCGA patient cohorts, COG5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,211 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COG5-associated genes across cancer lineages are GREM1, CYB561, and EARS2. Each is linked with COG5 in more than 5 cancer types. Because this analysis shows association rather than direction, both COG5-to-partner and partner-to-COG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COG5 versus GREM1 in GBM, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COG5→partner) and Y-score (partner→COG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GREM1 →	-1.296	-0.190	<.001	<.001	3	6
UCEC	CYB561 →	+0.902	+0.277	.001	<.001	3	6
BRCA	EARS2 →	+0.618	+0.317	<.001	<.001	3	6
GBM	PPP1R16B →	-1.691	-0.206	<.001	<.001	3	5
HNSC	DUSP26 →	-1.109	-0.118	.002	.005	3	5
UCEC	LDLRAD1 →	+1.551	+0.218	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,211 associations by consensus.

COG5 vs GREM1 — GBM

Explore this scatter interactively →