COG5

Across TCGA cell cohorts, COG5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,922 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COG5-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Vesicle transport along actin filament, and Peptidyl-serine phosphorylation. Each is linked with COG5 in more than 12 cancer types. Because this analysis shows association rather than direction, both COG5-to-partner and partner-to-COG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by COG5-low versus COG5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COG5→partner) and Y-score (partner→COG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Vesicle-mediated transport to the plasma membrane →	+0.047	+0.826	<.001	<.001	3	13
STOMACH	Vesicle transport along actin filament →	+0.258	+0.949	<.001	<.001	3	12
KIDNEY	Peptidyl-serine phosphorylation →	+0.084	+0.864	<.001	.005	3	12
KIDNEY	Peptidyl-serine modification →	+0.082	+0.854	.001	.006	3	12
LUNG_SCLC	Vesicle tethering →	+0.075	+0.536	.006	<.001	3	12
SOFT_TISSUE	Endocytic recycling →	+0.053	+0.813	.005	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,922 associations by consensus.

Vesicle-mediated transport to the plasma membrane by COG5 expression — SKIN

Explore this box plot interactively →