COG1

Across TCGA patient cohorts, COG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,873 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COG1-associated proteins across cancer lineages are ZFR, LIG3, and HNRNPLL. Each is linked with COG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COG1-to-partner and partner-to-COG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COG1 versus ZFR in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COG1→partner) and Y-score (partner→COG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZFR →	+0.281	+0.431	<.001	<.001	3	6
GBM	LIG3 →	+0.486	+0.404	<.001	<.001	3	5
GBM	HNRNPLL →	+0.316	+0.395	<.001	<.001	3	5
BRCA	VEZF1 →	+0.436	+0.425	<.001	.001	2	6
GBM	WRNIP1 →	+0.370	+0.353	<.001	<.001	3	5
LSCC	PRPF6 →	+0.321	+0.567	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,873 associations by consensus.

COG1 vs ZFR — GBM

Explore this scatter interactively →