COASY

Across TCGA cell cohorts, COASY RNA expression is significantly associated with the go_rna of many other GO terms, with 2,152 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible COASY-associated GO terms across cancer lineages are Aldehyde biosynthetic process, Glyceraldehyde-3-phosphate biosynthetic process, and Regulation of sterol biosynthetic process. Each is linked with COASY in more than 7 cancer types. Because this analysis shows association rather than direction, both COASY-to-partner and partner-to-COASY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldehyde biosynthetic process grouped by COASY-low versus COASY-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COASY→partner) and Y-score (partner→COASY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Aldehyde biosynthetic process →	+0.110	+0.531	.009	.001	2	8
LUNG_NSCLC_LUSC	Glyceraldehyde-3-phosphate biosynthetic process →	+0.131	+0.595	<.001	.001	3	6
LIVER	Regulation of sterol biosynthetic process →	+0.118	+0.606	.004	.007	3	6
URINARY_TRACT	Base-excision repair, gap-filling →	+0.092	+0.555	.004	.004	3	6
LIVER	Regulation of cholesterol biosynthetic process →	+0.118	+0.606	.004	.007	3	6
LUNG_SCLC	Protein-containing complex disassembly →	+0.044	+0.509	.007	.002	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,152 associations by consensus.

Aldehyde biosynthetic process by COASY expression — KIDNEY

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