COA4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COA4 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COA4-associated genes across cancer lineages are Chondrocytes. Each is linked with COA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both COA4-to-partner and partner-to-COA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocytes grouped by COA4-low versus COA4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COA4→partner) and Y-score (partner→COA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECChondrocytes →+0.014+3.286.005.04531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Chondrocytes by COA4 expression — UCEC

Box plot of Chondrocytes in COA4-low vs COA4-high samples in UCEC.

Explore this box plot interactively →

Exploration