CNTROB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNTROB protein abundance is significantly associated with the RNA expression of many other genes, with 7,196 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNTROB-associated genes across cancer lineages are CAMTA1, MAPKAP1, and SMG5. Each is linked with CNTROB in more than 3 cancer types. Because this analysis shows association rather than direction, both CNTROB-to-partner and partner-to-CNTROB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTROB versus CAMTA1 in GBM, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTROB→partner) and Y-score (partner→CNTROB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCAMTA1 →-0.554-0.247.003.00434
LSCCMAPKAP1 →-0.426-0.185<.001<.00134
LSCCSMG5 →-0.535-0.163<.001<.00134
LSCCTNPO3 →-0.432-0.142<.001.00134
UCECEIPR1 →-0.543-0.250.001<.00134
OVGINS3 →-0.619-0.638.006.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,196 associations by consensus.

CNTROB vs CAMTA1 — GBM

Per-sample scatter of CNTROB vs CAMTA1 in GBM (Pearson r = -0.27).

Explore this scatter interactively →

Exploration