CNTROB

Across TCGA cell cohorts, CNTROB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,521 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNTROB-associated GO terms across cancer lineages are Regulation of centriole-centriole cohesion, Mitotic centrosome separation, and Microtubule polymerization. Each is linked with CNTROB in more than 17 cancer types. Because this analysis shows association rather than direction, both CNTROB-to-partner and partner-to-CNTROB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole-centriole cohesion grouped by CNTROB-low versus CNTROB-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTROB→partner) and Y-score (partner→CNTROB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of centriole-centriole cohesion →	+0.220	+1.086	<.001	<.001	3	18
KIDNEY	Mitotic centrosome separation →	+0.126	+0.770	<.001	<.001	3	17
LARGE_INTESTINE	Microtubule polymerization →	+0.124	+0.939	<.001	<.001	3	17
URINARY_TRACT	Centrosome separation →	+0.153	+0.913	<.001	.002	3	17
BONE	Microtubule polymerization or depolymerization →	+0.112	+1.072	.001	<.001	3	17
SOFT_TISSUE	Centrosome duplication →	+0.098	+1.007	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,521 associations by consensus.

Regulation of centriole-centriole cohesion by CNTROB expression — URINARY_TRACT

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