CNTRL

Across TCGA patient cohorts, CNTRL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,222 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CNTRL-associated proteins across cancer lineages are PSIP1, SAP130, and XPA. Each is linked with CNTRL in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTRL-to-partner and partner-to-CNTRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTRL versus PSIP1 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTRL→partner) and Y-score (partner→CNTRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSIP1 →	+0.620	+0.434	<.001	<.001	3	5
GBM	SAP130 →	+0.312	+0.479	<.001	.001	3	5
GBM	XPA →	+0.339	+0.322	.001	.004	3	5
LSCC	BRD3 →	+0.390	+0.485	<.001	<.001	3	5
GBM	CELF2 →	+0.300	+0.430	<.001	.002	3	5
GBM	LMNB2 →	+0.395	+0.400	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,222 associations by consensus.

CNTRL vs PSIP1 — GBM

Explore this scatter interactively →