CNTRL

Across TCGA patient cohorts, CNTRL protein abundance is significantly associated with the RNA expression of many other genes, with 15,002 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNTRL-associated genes across cancer lineages are CSF2RB, GZMH, and VNN2. Each is linked with CNTRL in more than 6 cancer types. Because this analysis shows association rather than direction, both CNTRL-to-partner and partner-to-CNTRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTRL versus CSF2RB in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTRL→partner) and Y-score (partner→CNTRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CSF2RB →	+0.896	+0.300	<.001	.001	3	7
COAD	GZMH →	+2.446	+1.674	<.001	.004	3	7
PDAC	VNN2 →	+1.147	+0.684	<.001	<.001	3	7
BRCA	CD48 →	+1.124	+0.382	<.001	<.001	3	7
HNSC	GMFG →	+1.109	+0.261	<.001	.001	3	7
UCEC	DOCK2 →	+0.773	+0.314	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,002 associations by consensus.

CNTRL vs CSF2RB — GBM

Explore this scatter interactively →