CNTNAP3

Across TCGA patient cohorts, CNTNAP3 mutation is significantly associated with the RNA expression of many other genes, with 3,017 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTNAP3-associated genes across cancer lineages are RNA5SP528, MX1, and UBE2J2. Each is linked with CNTNAP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNTNAP3-to-partner and partner-to-CNTNAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP528 grouped by CNTNAP3-low versus CNTNAP3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP3→partner) and Y-score (partner→CNTNAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNA5SP528 →	+0.362	+4.758	<.001	.006	3	3
SKCM	MX1 →	-0.983	-2.405	.003	.003	3	3
UCEC	UBE2J2 →	+0.228	+1.617	.008	.001	3	3
UCEC	PPP2R2D →	+0.254	+1.818	.001	.001	3	3
UCEC	RPS6KB2 →	+0.335	+1.606	.001	.001	3	3
UCEC	CTDNEP1 →	+0.273	+1.668	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,017 associations by consensus.

RNA5SP528 by CNTNAP3 expression — LIHC

Explore this box plot interactively →