CNTNAP3

Across TCGA cell cohorts, CNTNAP3 mutation is significantly associated with the mutation status of many other genes, with 4,618 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTNAP3-associated genes across cancer lineages are RXFP1, PRUNE2, and ADGRD1. Each is linked with CNTNAP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTNAP3-to-partner and partner-to-CNTNAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RXFP1 grouped by CNTNAP3-low versus CNTNAP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP3→partner) and Y-score (partner→CNTNAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RXFP1 →	+3.247	+3.050	.008	.008	1	5
CNS	PRUNE2 →	+3.055	+3.786	.006	.006	1	4
CNS	ADGRD1 →	+5.277	+4.459	.005	.005	1	4
BLOOD_Leukemia	PNPLA5 →	+3.662	+3.285	.004	.004	1	4
SOFT_TISSUE	EIF3A →	+5.066	+4.502	.007	.007	1	4
SOFT_TISSUE	STAB2 →	+4.066	+5.022	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,618 associations by consensus.

RXFP1 by CNTNAP3 expression — BLOOD_Leukemia

Explore this box plot interactively →