CNTN6

Across TCGA patient cohorts, CNTN6 mutation is significantly associated with the RNA expression of many other genes, with 6,001 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTN6-associated genes across cancer lineages are TACC3, TRAIP, and POLE2. Each is linked with CNTN6 in more than 5 cancer types. Because this analysis shows association rather than direction, both CNTN6-to-partner and partner-to-CNTN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TACC3 grouped by CNTN6-low versus CNTN6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN6→partner) and Y-score (partner→CNTN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TACC3 →	+0.579	+1.725	<.001	<.001	3	6
STAD	TRAIP →	+0.414	+2.234	.009	.005	2	6
UCEC	POLE2 →	+0.423	+2.137	<.001	<.001	3	5
UCEC	CDKN3 →	+0.671	+1.595	<.001	<.001	3	5
LUSC	CINP →	+0.290	+2.105	.002	.003	3	5
UCEC	OIP5 →	+0.761	+2.406	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,001 associations by consensus.

TACC3 by CNTN6 expression — UCEC

Explore this box plot interactively →