CNTN4-AS1

Across TCGA pan-cancer cohorts, CNTN4-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CNTN4-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher CNTN4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CNTN4-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UVM, STAD, and UCS are the cancer types where CNTN4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Quartile	III,IV	0.264	0.743	.001	77	view →
STAD	OS	Median	All	0.350	0.627	<.001	44	view →
UCS	OS	Tertile	IV	0.844	0.250	.016	42	view →
OV	DFS	Quartile	All	0.321	0.400	.018	34	view →
BRCA	OS	Tertile	III,IV	0.914	0.794	.007	28	view →
KIRC	DFS	Median	III,IV	0.797	0.709	.009	19	view →
ESCA	OS	Median	III,IV	0.643	0.298	<.001	18	view →
PCPG	DFS	Quartile	All	0.561	0.904	<.001	18	view →
DLBC	OS	Tertile	IV	0.367	0.897	.018	18	view →
CESC	DFS	Tertile	All	0.854	0.712	.026	18	view →
KICH	DFS	Quartile	II,III,IV	0.348	0.900	.004	12	view →
KIRP	DFS	Tertile	II,III,IV	0.829	0.583	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CNTN4-AS1–UVM (OS)

Open the UVM breakdown →