CNTN4-AS1

Across TCGA pan-cancer cohorts, CNTN4-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CNTN4-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CNTN4-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CNTN4-AS1 is over-expressed in tumor, although a few such as LUSC and KIRC show the opposite, repressed pattern.

LUSC, KIRP, and KIRC are the cancer types where CNTN4-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNTN4-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.108	<.001	6	view →
KIRP	All	All	+0.046	.001	6	view →
KIRC	All	II,III,IV	−0.023	.001	6	view →
THCA	All	II,III,IV	−0.090	.010	4	view →
COAD	Female	All	−0.029	<.001	4	view →
UCEC	All	All	−0.186	.021	2	view →
LUAD	All	II,III,IV	−0.086	.009	2	view →
ESCA	All	II,III,IV	+0.055	.008	2	view →
PRAD	All	All	+0.044	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CNTN4-AS1–LUSC

Open the LUSC breakdown →