Across TCGA cell cohorts, CNTN2 mutation is significantly associated with the RNA expression of many other genes, with 972 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN2-associated genes across cancer lineages are PNLIPRP1, PES1, and HSPB8. Each is linked with CNTN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTN2-to-partner and partner-to-CNTN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN2→partner) and Y-score (partner→CNTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PNLIPRP1 →	+0.293	+4.321	<.001	.009	3	2
LARGE_INTESTINE	PES1 →	+0.440	+2.800	.009	.001	3	2
LARGE_INTESTINE	HSPB8 →	-1.083	-3.196	.009	.004	3	2
LARGE_INTESTINE	GMEB1 →	+0.666	+3.459	<.001	.001	3	2
LARGE_INTESTINE	ASMTL →	+0.616	+2.714	.003	.002	3	2
LARGE_INTESTINE	CDCA2 →	+0.854	+3.743	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 972 associations by consensus.

Exploration

CNTN2 survival (RNA) · tumor vs normal (RNA) · all CNTN2 data types