CNTLN

Across TCGA patient cohorts, CNTLN RNA expression is significantly associated with the protein abundance of many other proteins, with 15,319 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CNTLN-associated proteins across cancer lineages are PSIP1, CNTLN_S22, and HPF1. Each is linked with CNTLN in more than 7 cancer types. Because this analysis shows association rather than direction, both CNTLN-to-partner and partner-to-CNTLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTLN versus PSIP1 in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTLN→partner) and Y-score (partner→CNTLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSIP1 →	+0.610	+0.751	<.001	<.001	3	8
GBM	CNTLN_S22 →	+0.743	+0.657	<.001	<.001	3	6
GBM	HPF1 →	+0.386	+0.668	<.001	<.001	3	6
BRCA	VWA8 →	-0.402	-0.499	<.001	<.001	3	5
GBM	XAB2 →	+0.220	+0.631	.001	<.001	3	5
OV	CYC1 →	-0.658	-0.731	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,319 associations by consensus.

CNTLN vs PSIP1 — GBM

Explore this scatter interactively →