CNTLN

Across TCGA patient cohorts, CNTLN protein abundance is significantly associated with the RNA expression of many other genes, with 3,679 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CNTLN-associated genes across cancer lineages are G3BP2, CYP4X1, and ANK2-AS1. Each is linked with CNTLN in more than 2 cancer types. Because this analysis shows association rather than direction, both CNTLN-to-partner and partner-to-CNTLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTLN versus G3BP2 in UCEC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTLN→partner) and Y-score (partner→CNTLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	G3BP2 →	-0.474	-0.695	.001	.003	3	2
UCEC	CYP4X1 →	-0.988	-0.574	.007	.009	3	2
UCEC	ANK2-AS1 →	+0.859	+0.625	.003	.004	3	2
CCRCC	MAGI2-AS1 →	+1.093	+0.651	<.001	.002	3	2
UCEC	TPBGL →	+0.451	+0.570	<.001	.001	3	2
HNSC	RPL7P42 →	+0.351	+1.893	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,679 associations by consensus.

CNTLN vs G3BP2 — UCEC

Explore this scatter interactively →