CNTFR-AS1

Across TCGA pan-cancer cohorts, CNTFR-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CNTFR-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CNTFR-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNTFR-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

KIRC, UVM, and CHOL are the cancer types where CNTFR-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.548	0.754	<.001	150	view →
UVM	DFS	Quartile	All	0.271	0.712	<.001	72	view →
CHOL	OS	Tertile	II,III,IV	0.089	0.712	.006	72	view →
ACC	DFS	Tertile	All	0.039	0.778	<.001	66	view →
HNSC	DFS	Quartile	IV	0.510	0.260	<.001	45	view →
UCS	DFS	Median	III,IV	0.516	0.148	.003	30	view →
BRCA	OS	Median	III,IV	0.749	0.418	<.001	29	view →
THCA	DFS	Tertile	IV	0.486	0.900	.014	28	view →
BLCA	DFS	Tertile	All	0.249	0.374	.020	27	view →
SKCM	OS	Quartile	All	0.700	0.805	.006	25	view →
MESO	OS	Median	All	0.513	0.293	.002	19	view →
ESCA	OS	Median	All	0.777	0.608	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CNTFR-AS1–KIRC (DFS)

Open the KIRC breakdown →