CNTFR-AS1

Across TCGA pan-cancer cohorts, CNTFR-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CNTFR-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CNTFR-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CNTFR-AS1 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

BRCA, COAD, and UCEC are the cancer types where CNTFR-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNTFR-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.617	<.001	6	view →
COAD	Female	II,III,IV	−0.190	<.001	6	view →
UCEC	All	IV	−0.295	.002	2	view →
BLCA	Female	All	+0.038	.019	2	view →
CHOL	All	All	−0.094	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CNTFR-AS1–BRCA

Open the BRCA breakdown →