CNTD1

Across TCGA patient cohorts, CNTD1 mutation is significantly associated with the RNA expression of many other genes, with 454 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTD1-associated genes across cancer lineages are RNU1-105P, APOOP2, and RN7SKP14. Each is linked with CNTD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTD1-to-partner and partner-to-CNTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-105P grouped by CNTD1-low versus CNTD1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTD1→partner) and Y-score (partner→CNTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-105P →	+0.346	+6.584	<.001	<.001	3	2
LUAD	APOOP2 →	+0.294	+4.990	<.001	.009	3	2
SKCM	RN7SKP14 →	+0.065	+4.993	<.001	.002	3	2
SKCM	SDHDP1 →	+0.066	+4.292	<.001	.001	3	2
UCEC	IGHV3OR16-8 →	+0.728	+2.687	<.001	.001	3	1
UCEC	RPL23AP90 →	+0.287	+2.556	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 454 associations by consensus.

RNU1-105P by CNTD1 expression — CESC

Explore this box plot interactively →