CNTD1

Across TCGA pan-cancer cohorts, CNTD1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CNTD1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CNTD1 RNA is repressed in tumor relative to normal tissue. In most cancer types CNTD1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, LIHC, and KICH are the cancer types where CNTD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNTD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.897	<.001	12	view →
LIHC	Female	II,III,IV	+0.361	<.001	8	view →
KICH	Male	All	−0.998	<.001	7	view →
BLCA	All	All	+0.332	.002	7	view →
COAD	All	II,III,IV	+0.433	<.001	6	view →
CHOL	Male	All	+1.190	<.001	5	view →
KIRP	Male	All	−0.572	.001	4	view →
LUSC	All	All	−0.255	.013	3	view →
READ	Female	All	+0.900	.010	2	view →
PRAD	All	All	+0.395	.005	2	view →
STAD	Male	IV	−0.454	.003	1	view →
HNSC	Male	III,IV	+0.143	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CNTD1–KIRC

Open the KIRC breakdown →