CNTD1

Across TCGA patient cohorts, CNTD1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTD1-associated genes across cancer lineages are eEF2, A-Raf_pS299, and GAPDH. Each is linked with CNTD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTD1-to-partner and partner-to-CNTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CNTD1-low versus CNTD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTD1→partner) and Y-score (partner→CNTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.523	+3.000	.001	.036	3	1
UCEC	A-Raf_pS299 →	-0.127	-3.169	.022	.019	3	1
UCEC	GAPDH →	+0.786	+3.321	.001	.009	3	1
UCEC	GATA6 →	-0.201	-3.577	.006	.002	3	1
UCEC	Heregulin →	-0.142	-2.584	.013	.011	3	1
UCEC	MIG-6 →	+0.127	+2.331	.006	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

eEF2 by CNTD1 expression — UCEC

Explore this box plot interactively →