CNR1

Across TCGA cell cohorts, CNR1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNR1-associated genes across cancer lineages are OR10R2, OR2G6, and DEFA4. Each is linked with CNR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNR1-to-partner and partner-to-CNR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by CNR1-low versus CNR1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNR1→partner) and Y-score (partner→CNR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10R2 →	+1.281	+4.551	.006	.004	3	2
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ACSM6 →	+0.023	+3.658	<.001	.005	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
BLOOD_Leukemia	C1orf158 →	+0.161	+4.276	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR10R2 by CNR1 expression — BLOOD_Leukemia

Explore this box plot interactively →