CNPPD1

Across TCGA patient cohorts, CNPPD1 mutation is significantly associated with the RNA expression of many other genes, with 900 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNPPD1-associated genes across cancer lineages are CTBP2P9, GPX6, and MTHFD2P7. Each is linked with CNPPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNPPD1-to-partner and partner-to-CNPPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTBP2P9 grouped by CNPPD1-low versus CNPPD1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPPD1→partner) and Y-score (partner→CNPPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	CTBP2P9 →	+0.052	+6.257	<.001	.001	3	2
COAD	GPX6 →	+0.175	+5.435	<.001	.005	3	2
UCEC	MTHFD2P7 →	+0.142	+2.517	.005	.001	3	2
LIHC	RN7SL402P →	+0.230	+5.447	<.001	.005	3	2
SKCM	MRPS6P4 →	+0.081	+4.199	<.001	.009	3	2
READ	RNGTTP1 →	+0.121	+5.421	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 900 associations by consensus.

CTBP2P9 by CNPPD1 expression — READ

Explore this box plot interactively →