CNPPD1

Across TCGA cell cohorts, CNPPD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,758 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNPPD1-associated GO terms across cancer lineages are Methylglyoxal metabolic process, Cytosolic transport, and Mitochondrial tRNA methylation. Each is linked with CNPPD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CNPPD1-to-partner and partner-to-CNPPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylglyoxal metabolic process grouped by CNPPD1-low versus CNPPD1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPPD1→partner) and Y-score (partner→CNPPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Methylglyoxal metabolic process →	+0.119	+0.591	<.001	<.001	3	12
SKIN	Cytosolic transport →	+0.066	+0.523	<.001	.005	2	12
LUNG_NSCLC_LUSC	Mitochondrial tRNA methylation →	-0.138	-0.795	<.001	<.001	3	11
SKIN	Cellular response to methylglyoxal →	+0.163	+0.705	<.001	<.001	3	11
SKIN	Cellular detoxification of methylglyoxal →	+0.163	+0.705	<.001	<.001	3	11
SKIN	Response to methylglyoxal →	+0.163	+0.705	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,758 associations by consensus.

Methylglyoxal metabolic process by CNPPD1 expression — SKIN

Explore this box plot interactively →