CNOT4

Across TCGA cell cohorts, CNOT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,274 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNOT4-associated GO terms across cancer lineages are Peptidyl-serine phosphorylation, Regulation of translational initiation, and Peptidyl-serine modification. Each is linked with CNOT4 in more than 13 cancer types. Because this analysis shows association rather than direction, both CNOT4-to-partner and partner-to-CNOT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine phosphorylation grouped by CNOT4-low versus CNOT4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT4→partner) and Y-score (partner→CNOT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Peptidyl-serine phosphorylation →	+0.090	+0.575	<.001	.003	2	14
LARGE_INTESTINE	Regulation of translational initiation →	+0.066	+0.363	.001	.006	3	13
KIDNEY	Peptidyl-serine modification →	+0.089	+0.571	<.001	.003	2	13
BLOOD_Lymphoma	RNA destabilization →	+0.052	+0.439	<.001	.005	3	12
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.066	+0.579	<.001	<.001	3	12
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.137	+0.427	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,274 associations by consensus.

Peptidyl-serine phosphorylation by CNOT4 expression — KIDNEY

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