CNOT10-AS1

Across TCGA patient cohorts, CNOT10-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,471 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNOT10-AS1-associated proteins across cancer lineages are TOP2B, HDAC2, and SMCHD1. Each is linked with CNOT10-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNOT10-AS1-to-partner and partner-to-CNOT10-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT10-AS1 versus TOP2B in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT10-AS1→partner) and Y-score (partner→CNOT10-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOP2B →	+0.366	+0.555	.001	.003	3	5
OV	HDAC2 →	+0.734	+0.298	.002	.008	3	4
GBM	SMCHD1 →	+0.304	+0.613	<.001	<.001	3	4
PDAC	THOC2_T1443 →	+0.440	+0.433	.008	.001	3	3
GBM	NONO →	+0.218	+0.753	<.001	<.001	3	3
GBM	NXF1 →	+0.214	+0.394	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,471 associations by consensus.

CNOT10-AS1 vs TOP2B — LSCC

Explore this scatter interactively →