CNNM4

Across TCGA patient cohorts, CNNM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,971 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNNM4-associated proteins across cancer lineages are MTA3, HEXIM1, and FKBP11. Each is linked with CNNM4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNNM4-to-partner and partner-to-CNNM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM4 versus MTA3 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM4→partner) and Y-score (partner→CNNM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA3 →	+0.407	+0.463	<.001	<.001	3	5
UCEC	HEXIM1 →	+0.392	+0.616	<.001	.002	3	5
BRCA	FKBP11 →	-0.681	-0.801	<.001	<.001	3	5
BRCA	KAT8 →	+0.271	+0.564	.001	.001	3	5
LSCC	RBBP6 →	+0.209	+0.315	.002	.004	3	4
UCEC	NOL10 →	+0.354	+0.465	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,971 associations by consensus.

CNNM4 vs MTA3 — LSCC

Explore this scatter interactively →