CNNM4

Across TCGA patient cohorts, CNNM4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,912 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNNM4-associated genes across cancer lineages are BCL6B, FLT3, and CNRIP1. Each is linked with CNNM4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNNM4-to-partner and partner-to-CNNM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM4 versus BCL6B in UCEC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM4→partner) and Y-score (partner→CNNM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCL6B →	-0.694	-0.565	<.001	<.001	3	5
HNSC	FLT3 →	-0.887	-0.297	<.001	<.001	3	5
UCEC	CNRIP1 →	-0.942	-0.527	<.001	<.001	3	4
UCEC	SYNE1 →	-0.687	-0.408	<.001	<.001	3	4
CCRCC	ENTPD1 →	-0.458	-0.430	<.001	.001	3	4
UCEC	PLCL2 →	-0.690	-0.398	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,912 associations by consensus.

CNNM4 vs BCL6B — UCEC

Explore this scatter interactively →