CNNM4

Across TCGA cell cohorts, CNNM4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,296 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CNNM4-associated genes across cancer lineages are KANSL3, CNNM3, and INPP4A. Each is linked with CNNM4 in more than 15 cancer types. Because this analysis shows association rather than direction, both CNNM4-to-partner and partner-to-CNNM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM4 versus KANSL3 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.65.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM4→partner) and Y-score (partner→CNNM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	KANSL3 →	+1.005	+1.137	<.001	<.001	3	16
BONE	CNNM3 →	+1.308	+1.162	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	INPP4A →	+1.154	+1.094	<.001	<.001	3	13
BONE	MBD5 →	+0.976	+0.758	<.001	<.001	3	12
STOMACH	CMTM4 →	+1.357	+0.668	<.001	.006	2	13
UPPER_AERODIGESTIVE_TRACT	ADAR →	+1.222	+1.212	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,296 associations by consensus.

CNNM4 vs KANSL3 — UPPER_AERODIGESTIVE_TRACT

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