CNNM4

Across TCGA cell cohorts, CNNM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,912 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CNNM4-associated GO terms across cancer lineages are Magnesium ion homeostasis, Magnesium ion transport, and Magnesium ion transmembrane transport. Each is linked with CNNM4 in more than 17 cancer types. Because this analysis shows association rather than direction, both CNNM4-to-partner and partner-to-CNNM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Magnesium ion homeostasis grouped by CNNM4-low versus CNNM4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM4→partner) and Y-score (partner→CNNM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Magnesium ion homeostasis →	+0.114	+1.247	.005	<.001	3	18
CNS	Magnesium ion transport →	+0.110	+0.710	<.001	<.001	3	14
CNS	Magnesium ion transmembrane transport →	+0.110	+0.710	<.001	<.001	3	14
OVARY	Glycerophospholipid metabolic process →	+0.037	+0.963	<.001	<.001	3	13
OVARY	Phospholipid biosynthetic process →	+0.041	+1.052	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Glycerolipid biosynthetic process →	+0.039	+0.833	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

Magnesium ion homeostasis by CNNM4 expression — OESOPHAGUS

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