CNNM3

Across TCGA patient cohorts, CNNM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNNM3-associated proteins across cancer lineages are SIN3A, HNRNPU, and MYEF2. Each is linked with CNNM3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CNNM3-to-partner and partner-to-CNNM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM3 versus SIN3A in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM3→partner) and Y-score (partner→CNNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIN3A →	+0.275	+0.337	<.001	<.001	3	8
LSCC	HNRNPU →	+0.286	+0.575	<.001	<.001	3	8
BRCA	MYEF2 →	+0.811	+0.680	<.001	<.001	3	7
BRCA	NRBF2 →	-0.414	-0.606	<.001	.001	3	7
LSCC	PRPF4 →	+0.306	+0.545	<.001	<.001	3	7
GBM	SMARCC2 →	+0.304	+0.374	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,926 associations by consensus.

CNNM3 vs SIN3A — GBM

Explore this scatter interactively →