CNNM3

Across TCGA patient cohorts, CNNM3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,485 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CNNM3-associated genes across cancer lineages are COL6A3, OSER1-DT, and RAB3IL1. Each is linked with CNNM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CNNM3-to-partner and partner-to-CNNM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM3 versus COL6A3 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM3→partner) and Y-score (partner→CNNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL6A3 →	-1.294	-0.203	.003	.006	3	6
BRCA	OSER1-DT →	+0.571	+0.377	<.001	.003	3	5
LSCC	RAB3IL1 →	-0.628	-0.248	<.001	.001	3	5
BRCA	SAMD15 →	+0.874	+0.365	<.001	<.001	3	4
HNSC	ARFGEF3 →	+1.104	+0.272	<.001	<.001	3	4
LUAD	ELAPOR1 →	+1.932	+0.295	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,485 associations by consensus.

CNNM3 vs COL6A3 — GBM

Explore this scatter interactively →