CNNM2

Across TCGA cell cohorts, CNNM2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,696 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNNM2-associated genes across cancer lineages are NDST2, HIF1AN, and SEC24C. Each is linked with CNNM2 in more than 15 cancer types. Because this analysis shows association rather than direction, both CNNM2-to-partner and partner-to-CNNM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM2 versus NDST2 in KIDNEY, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM2→partner) and Y-score (partner→CNNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	NDST2 →	+0.943	+0.878	.001	.002	3	16
BONE	HIF1AN →	+0.934	+0.962	<.001	<.001	3	15
BLOOD_Lymphoma	SEC24C →	+0.797	+0.606	<.001	<.001	3	14
KIDNEY	GBF1 →	+0.903	+0.879	.005	.001	2	15
STOMACH	ZRANB1 →	+1.106	+1.216	<.001	<.001	3	14
OESOPHAGUS	POLL →	+0.808	+0.717	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,696 associations by consensus.

CNNM2 vs NDST2 — KIDNEY

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