CNNM1

Across TCGA pan-cancer cohorts, CNNM1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CNNM1 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CNNM1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNNM1 expression acts as an unfavorable survival marker.

OV, LUAD, and CESC are the cancer types where CNNM1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	II,III,IV	0.233	0.541	.033	24	view →
LUAD	OS	Median	All	0.312	0.688	<.001	16	view →
CESC	OS	Median	All	0.456	0.802	.001	12	view →
BLCA	OS	Median	III,IV	0.117	0.684	<.001	12	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →
SKCM	DFS	Median	IV	0.036	0.433	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CNNM1–OV (DFS)

Open the OV breakdown →