CNMD

Across TCGA cell cohorts, CNMD mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNMD-associated genes across cancer lineages are DYNAP and FAM205A. Each is linked with CNMD in more than 1 cancer types. Because this analysis shows association rather than direction, both CNMD-to-partner and partner-to-CNMD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYNAP grouped by CNMD-low versus CNMD-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNMD→partner) and Y-score (partner→CNMD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DYNAP →	+0.126	+4.867	<.001	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.030	+5.029	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DYNAP by CNMD expression — BLOOD_Lymphoma

Explore this box plot interactively →