CNKSR3

Across TCGA patient cohorts, CNKSR3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,208 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNKSR3-associated genes across cancer lineages are NFATC2, NBN, and DECR1. Each is linked with CNKSR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNKSR3-to-partner and partner-to-CNKSR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR3 versus NFATC2 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR3→partner) and Y-score (partner→CNKSR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NFATC2 →	-0.705	-0.289	.002	.008	3	2
LSCC	NBN →	+0.411	+0.326	<.001	<.001	3	2
LSCC	DECR1 →	+0.702	+0.504	<.001	<.001	3	2
LSCC	COX6A1 →	+0.629	+0.445	.001	.001	3	2
CCRCC	CISD1 →	+0.680	+0.763	<.001	<.001	3	2
CCRCC	ACE2 →	+1.387	+0.609	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,208 associations by consensus.

CNKSR3 vs NFATC2 — HNSC

Explore this scatter interactively →