CNKSR3

Across TCGA cell cohorts, CNKSR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,623 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNKSR3-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Negative regulation of peptidyl-serine phosphorylation, and PML body organization. Each is linked with CNKSR3 in more than 9 cancer types. Because this analysis shows association rather than direction, both CNKSR3-to-partner and partner-to-CNKSR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by CNKSR3-low versus CNKSR3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR3→partner) and Y-score (partner→CNKSR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Phospholipid biosynthetic process →	+0.046	+1.444	.008	.005	2	10
BONE	Negative regulation of peptidyl-serine phosphorylation →	+0.152	+1.390	<.001	<.001	3	9
OVARY	PML body organization →	+0.182	+1.241	<.001	<.001	3	9
BREAST	Regulation of translational initiation →	+0.053	+1.499	<.001	<.001	3	8
BONE	Protein targeting to vacuole involved in autophagy →	+0.168	+1.185	<.001	.004	3	8
SOFT_TISSUE	Regulation of DNA-templated transcription initiation →	+0.055	+0.974	.002	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,623 associations by consensus.

Phospholipid biosynthetic process by CNKSR3 expression — STOMACH

Explore this box plot interactively →