CNKSR1

Across TCGA patient cohorts, CNKSR1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,908 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CNKSR1-associated genes across cancer lineages are TMEM50A, MFN2, and FAM160A1-DT. Each is linked with CNKSR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNKSR1-to-partner and partner-to-CNKSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR1 versus TMEM50A in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR1→partner) and Y-score (partner→CNKSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TMEM50A →	+0.486	+0.380	<.001	<.001	3	4
LSCC	MFN2 →	+0.495	+0.307	<.001	<.001	3	4
BRCA	FAM160A1-DT →	+0.962	+0.482	<.001	<.001	3	4
HNSC	TTC7B →	-0.459	-0.330	.001	<.001	3	3
UCEC	KIRREL1 →	-0.609	-0.309	.002	.002	3	3
LUAD	PPP2R5A →	+0.664	+0.332	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,908 associations by consensus.

CNKSR1 vs TMEM50A — LUAD

Explore this scatter interactively →