CNIH4

Across TCGA patient cohorts, CNIH4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,510 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNIH4-associated proteins across cancer lineages are C1orf35, CACYBP, and ADSS2. Each is linked with CNIH4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CNIH4-to-partner and partner-to-CNIH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNIH4 versus C1orf35 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH4→partner) and Y-score (partner→CNIH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C1orf35 →	+0.393	+0.513	<.001	<.001	3	6
UCEC	CACYBP →	+0.445	+0.730	<.001	<.001	3	6
BRCA	ADSS2 →	+0.290	+0.481	.001	.001	3	6
OV	ANP32E →	+0.660	+0.545	<.001	<.001	3	6
BRCA	RPRD2 →	+0.266	+0.449	<.001	<.001	3	5
BRCA	STARD5 →	-0.501	-0.646	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,510 associations by consensus.

CNIH4 vs C1orf35 — LSCC

Explore this scatter interactively →