CNIH4

Across TCGA patient cohorts, CNIH4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,148 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CNIH4-associated genes across cancer lineages are HBA2, LINC00519, and EXOC8. Each is linked with CNIH4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNIH4-to-partner and partner-to-CNIH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNIH4 versus HBA2 in CCRCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH4→partner) and Y-score (partner→CNIH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HBA2 →	+1.503	+0.360	<.001	<.001	3	4
LSCC	LINC00519 →	+0.820	+0.169	.001	.002	3	3
LSCC	EXOC8 →	+0.389	+0.283	<.001	<.001	3	2
UCEC	ADGRE5 →	-0.981	-0.419	<.001	<.001	3	2
UCEC	CETN2 →	-0.991	-0.420	.005	<.001	3	2
UCEC	CHST9 →	+0.696	+0.299	.006	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

CNIH4 vs HBA2 — CCRCC

Explore this scatter interactively →