CNIH4

Across TCGA cell cohorts, CNIH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,000 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNIH4-associated GO terms across cancer lineages are Mitotic nuclear membrane organization, Geranyl diphosphate metabolic process, and Mitotic nuclear membrane reassembly. Each is linked with CNIH4 in more than 8 cancer types. Because this analysis shows association rather than direction, both CNIH4-to-partner and partner-to-CNIH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear membrane organization grouped by CNIH4-low versus CNIH4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH4→partner) and Y-score (partner→CNIH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Mitotic nuclear membrane organization →	+0.141	+0.736	<.001	<.001	3	9
KIDNEY	Geranyl diphosphate metabolic process →	+0.130	+0.691	<.001	<.001	3	9
LIVER	Mitotic nuclear membrane reassembly →	+0.141	+0.736	<.001	<.001	3	9
CNS	Positive regulation of endoplasmic reticulum tubular network organization →	+0.098	+0.590	<.001	.001	3	7
BLOOD_Lymphoma	Nuclear membrane organization →	+0.093	+1.023	<.001	<.001	3	7
BLOOD_Myeloma	Tubulin complex assembly →	+0.113	+1.110	.005	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,000 associations by consensus.

Mitotic nuclear membrane organization by CNIH4 expression — LIVER

Explore this box plot interactively →