CNIH3-AS2

Across TCGA pan-cancer cohorts, CNIH3-AS2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CNIH3-AS2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CNIH3-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CNIH3-AS2 expression acts as an unfavorable survival marker, although some lineages such as KIRP and ESCA show a favorable association.

MESO, UVM, and KIRC are the cancer types where CNIH3-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.428	0.656	<.001	138	view →
UVM	DFS	Median	All	0.417	0.766	<.001	119	view →
KIRC	DFS	Median	All	0.511	0.696	<.001	113	view →
LGG	OS	Median	All	0.739	0.879	<.001	38	view →
KIRP	OS	Tertile	All	0.979	0.835	.001	31	view →
UCS	DFS	Tertile	IV	0.237	0.818	.024	30	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	27	view →
UCEC	OS	Quartile	All	0.825	0.919	.003	22	view →
THCA	DFS	Median	All	0.776	0.899	.004	22	view →
ESCA	DFS	Quartile	All	0.739	0.457	.006	14	view →
SARC	OS	Median	All	0.627	0.812	.002	14	view →
READ	DFS	Quartile	IV	0.214	0.771	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CNIH3-AS2–MESO (OS)

Open the MESO breakdown →