CNIH2

Across TCGA patient cohorts, CNIH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,626 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNIH2-associated proteins across cancer lineages are MTA1_S576, TOP2A, and TPX2. Each is linked with CNIH2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNIH2-to-partner and partner-to-CNIH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNIH2 versus MTA1_S576 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH2→partner) and Y-score (partner→CNIH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA1_S576 →	+0.949	+0.717	<.001	<.001	3	5
LSCC	TOP2A →	+0.762	+0.558	<.001	<.001	3	4
LSCC	TPX2 →	+0.782	+0.778	<.001	<.001	3	4
LSCC	POLD1 →	+0.465	+0.702	<.001	<.001	3	4
LSCC	NASP →	+0.603	+0.721	<.001	<.001	3	4
GBM	NSD2 →	+0.409	+0.744	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,626 associations by consensus.

CNIH2 vs MTA1_S576 — LSCC

Explore this scatter interactively →