CNGB1

Across TCGA patient cohorts, CNGB1 mutation is significantly associated with the RNA expression of many other genes, with 7,698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNGB1-associated genes across cancer lineages are TIPIN, RPARP-AS1, and PMM2P2. Each is linked with CNGB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNGB1-to-partner and partner-to-CNGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIPIN grouped by CNGB1-low versus CNGB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGB1→partner) and Y-score (partner→CNGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.572	+2.928	<.001	<.001	3	4
UCEC	RPARP-AS1 →	+0.408	+2.000	<.001	<.001	3	3
CESC	PMM2P2 →	+0.077	+4.349	<.001	<.001	3	3
READ	MIR588 →	+0.558	+6.681	<.001	<.001	3	3
UCEC	APTX →	+0.352	+2.458	<.001	<.001	3	3
UCEC	BAG3 →	+0.484	+2.179	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,698 associations by consensus.

TIPIN by CNGB1 expression — UCEC

Explore this box plot interactively →